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Retatrutide titration protocol Retatrutide follows a similar monthly escalation pattern, but with different starting points and targets: Weeks 1-4: 1mg once weekly (initiation) Weeks 5-8: 2mg once weekly Weeks 9-12: 4mg once weekly Weeks 13-16: 8mg once weekly Week 17+: 12mg once weekly (maintenance) The retatrutide starting dose is lower at 1mg, reflecting the triple agonist mechanism and the need for careful GI adjustment
People expect immediate results because they know the medication is in their body
however, all four participants with SAEs were in the placebo group, with the participant with SUSAR in the semaglutide group
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