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Patients who switched were more likely to continue treatment and showed higher adherence than those who remained on their initial medication, suggesting adjustments often reflected active management
The first reaction is catalyzed by tryptophan hydroxylase (TPH-1), which requires L-tryptophan, tetrahydrobiopterin (BH4), and O 2 as co-substrates, and has ferrous ion (Fe 2+ ) as an activator
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La carnitina se produce en el hgado y en rin a partir de la sintetizacin de los aminocidos lisina y metionina
Dose escalation
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