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Treatment begins with an initiation dose of 0.25 mg, administered once weekly for the first four weeks
Contact your healthcare provider if the vomiting is severe or does not subside
Risk ratios (RR) for hospitalization for heart failure estimates according to direct (DPP-4 inhibitors, GLP-1RA and SGLT-2 inhibitors against placebo) and indirect (DPP-4 inhibitors vs GLP-1RA or SGLT-2 inhibitors, and GLP-1RA vs SGLT-2 inhibitors) comparisons
This suggests that staying on treatment, not reaching the highest dose fastest, is the critical variable for success
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