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Reconstitution: IGF-1 DES is typically sold as lyophilized powder requiring reconstitution with bacteriostatic water

It contains the highest concentration of leucine, the amino acid that triggers muscle protein synthesis

These numbers line up closely with what is seen in Semaglutide and Tirzepatide trials at similar timepoints, which is reassuring given that both of those compounds have now accumulated years of post-market surveillance data

Caroline Apovian, co-director of the Center for Weight Management and Wellness at Brigham and Women's Hospital, has stated: "Any patient losing more than 15 percent of body weight on pharmacotherapy should be treated with the same nutritional vigilance we apply to post-bariatric surgery patients" [10]