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Whether iron overload or deficiency, it will affect the differentiation and activity of osteoclasts and osteoblasts, thereby disrupting the bone homeostasis and accelerating bone loss

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Glia 54:873879 Liddell JR, Hoepken HH, Crack PJ, Robinson SR, Dringen R (2006b) Glutathione peroxidase 1 and glutathione are required to protect mouse astrocytes from iron-mediated hydrogen peroxide toxicity