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Acknowledgments The authors express their thanks to Drs Eckhardt Ferdinandi and Claude Larose (formerly of Theratechnologies Inc.) for providing the GLP-1 receptors agonists labelled above as G001 and G002, to Olga Plaskon, Estera Karolczyk, Kasia Zajkowska and Gurpal Bansal for technical assistance, and to Professor Huw Jones, Middlesex University for help with statistical analyses

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In its Complete Response Letter on Tuesday, the FDA indicated that it was continuing to review safety data for Ocaliva from one of its confirmatory studies