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Exploratory endpoints reported included changes from baseline to week 104 in glycemic category, antihypertensive medication use, and lipid-lowering medication use
[1] [2] This weekly dosing schedule is consistent with other long-acting incretin-based therapies and is designed to maintain stable plasma drug concentrations throughout the week, minimising peaks and troughs that could exacerbate side effects
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If gastrointestinal side effects are intolerable despite optimal management, discontinuation may be appropriate, and your healthcare team can discuss alternative treatment options
(Clinical Pharmacologist) writes: Some Additional Insight into Bioavailability and Pharmacology Bioavailability is a measure of both the rate of absorption and the extent of absorption
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