It's a trace mineral involved in several enzyme systems that help process sulfur-containing compounds, including sulfites.47 Because NAC itself is a sulfur-containing molecule, there's a reasonable biological rationale for pairing the two ingredients
They work by: Enhancing insulin secretion in response to meals Reducing glucagon secretion (which helps lower blood sugar levels) Slowing gastric emptying, leading to increased satiety The efficacy of GLP-1 medications has led to their FDA approval for weight management, making them an attractive option for many individuals seeking to lose weight
(PubMed) Gomez-Sierra T, Molina-Jijon E, Tapia E, et al
The logistical problems could lead to even more time off the medications
[5] This outperformance of two established dermatological actives is notable, though the study methodology, blinding procedures, and outcome measurement techniques are not described in the level of detail that independent peer review would demand