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Health Canada has not approved retatrutide for clinical use

A network meta-analysis reported that the incidence of DR outcomes, including DR, macular edema, vitreous hemorrhage, diabetes-related blindness, and treatment of intravitreal agent, retinal photocoagulation, and vitrectomy, were comparable not only between patients receiving SGLT2i and placebo (odds ratio [OR], 0.79

Still, keep these safety tips in mind: Follow Recommended Dosages: More is not always better

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65% of Americans name it as the most relevant reason