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[8] There is no structured nutrition program, accountability system, or community layer built into care
Safety Considerations and Future Outlook As with all pharmacotherapy for obesity and T2D, establishing cardiovascular safety and demonstrating improvements in meaningful clinical outcomes will be essential, particularly as cardiovascular outcome trials have not yet been completed with multi-agonists (although data are expected soon for tirzepatide: SURPASS-CVOT [T2D] in 2025
Early satiety during meals is common
Weight Loss Results Are Stronger with Injectables When it comes to weight loss, injectable GLP-1s are currently unmatched
Interestingly, a meta-analysis of studies on overweight hypertensive individuals without diabetes reported that semaglutide treatment can lead to a significant reduction in blood pressure
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