Recombinant Human Heparin-binding EGF-like Growth Factor (Human HB-EGF)_C230367 Size:100 μg < 1 EU per 1μg

< 1 EU per 1μg of the protein by the LAL method

As a member of the tumor necrosis factor receptor (TNFR) superfamily of proteins

including a 28 amino acid cytoplasmic region

Therapeutic doses of the anticoagulant heparin neutralize CXCL4 procoagulant effects

with 3 % Trehalose

Recombinant Human Heparin-binding EGF-like Growth Factor (Human HB-EGF)_C230367 Size:100 μg < 1 EU per 1μgHuman HB EGF (Heparin Binding EGF like growth factor), also known as the DTR (diphtheria toxin receptor), is a 12 16 kDa member of the EGF family of peptide growth factors. It is further classified as a group 2 ErbB ligand based on its ability to activate both the EGF ErbB1 and ErbB4 receptors. Mature HB EGF is a soluble peptide that arises from proteolytic processing of the transmembrane form. The transmembrane form of HBEGF is a juxtacrine growth