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"People who have alcohol use disorder get an internal brain reward for drinking, and we think that the semaglutide removes at least part of that sense of being rewarded for taking a drink." Though the research is promising, Xu said it's merely an observational study from clinical trials, meaning more research is needed before her team makes any recommendations for prescribing semaglutide for substance use treatment

The glucagon receptor component is interesting here because glucagon normally raises blood sugar

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Phosphatidylcholine for steroid-refractory chronic ulcerative colitis: a randomized trial