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SIRT1 is linked to circadian rhythms and cellular mechanisms, such as cell repair, division, metabolism, and growth (20)
It is also worth noting that clinical trial populations are carefully selected and monitored participants with significant pre-existing gastrointestinal disease are typically excluded and real-world rates of nausea may differ once a medicine reaches broader clinical use
Romero-Gmez M, Lawitz E, Shankar RR, Chaudhri E, Liu J, Lam RLH, et al
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