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Bioavailability Varies by compound many peptides are largely broken down in the gut, so little reaches the blood intact

There are two types of GHS studied in the scientific literature: peptide GHS and non-peptide compounds

During the focused PK studies, n = 3 CD-1 mice were euthanized per time point ( t = 0.5, 1, 2, 4, 8 and 24 h post administration) to conduct a stomach and a small intestine lavage, to collect whole blood from the heart, urine, faeces, stomach, small intestine and colon

Chest (2009) 135(1):17380

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