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External resources for researchers PubChem 5-Amino-1-methylquinolinium Open-access paper selective small-molecule NNMT inhibitors PubMed NNMT inhibition in preclinical metabolic research Related research products Disclaimer Used solely for in vitro experiments and cannot be: Used in clinical trials involving humans Administered to humans as part of an experiment or investigation Supplied to another party for human investigational use

By attenuating NNMT activity, 5Amino1MQ has been observed in preclinical settings to elevate NAD+ availability, enhance metabolic flux, and upregulate downstream signaling programs associated with cellular stress responses and energy expenditure (e.g., SIRT1)

This increase in energy might lead to more physical activity, like exercise, helping you burn more calories