A five-year, randomized, double-blind, placebo-controlled trial in healthy Danish older people (ages at inclusion, 60-74 years) found that selenium supplementation (100-300 g/day) had little-to-no impact on circulating levels of antioxidant enzymes, including GPx (166)
Melanie Avalon Exactly, which I know is why, like mentioning David Sinclair, his book Lifespan, he talks about how he really champions the idea of aging being a disease, because if it's a disease, then you can, then you could do more trials for it, because you'd have something that you could work towards that's verifiable as a disease
Cost is one of the most-searched aspects of this treatment and it varies widely
Pioglitazone and the secondary prevention of cardiovascular disease
F., Leong, K