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Starting with both peptides together makes it difficult to assess individual responses, but the strong safety profiles of both compounds make this a minor concern

For example, decreased sodium excretion (increasing levels) results in water retention and a condition known as volume overload, which causes swelling of tissues (edema)

In addition, HTY has been linked with improved endothelial function by supporting nitric oxide production, which may improve blood flow and contribute to blood pressure regulation

McCullough KD, Martindale JL, Klotz LO, Aw TY, Holbrook NJ

For full protocol detail, including reconstitution volumes, post-reconstitution storage windows, and research administration schedules, see our full BPC-157 + TB-500 dosing protocol