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At the 4-h time point, serum levels of alanine transaminase and aspartate transaminase (AST) were markedly higher in the hepsin / mice, indicating more severe liver damage compared with their wild-type counterparts (Fig

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This oxidative crisis leads to red blood cell destruction, a key concern in malaria treatment and CSIR NET life sciences exams. Primaquine Mechanism in Hemolysis Primaquine treats Plasmodium vivax relapses but its quinone metabolites like 5,6-POQ generate ROS, oxidizing hemoglobin and GSH

Levels of tGSH in the TIF were much higher than reported amounts added to formulations of cell culture media (Extended Data Fig

Selectivity versus selective agonists The non-selective profile separates MT-II from clinically derived analogues