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Results: MTX altered the concentration of 31 out of 70 metabolites analyzed, suggesting inhibition of the glycine cleavage system, the pentose phosphate pathway, purine and pyrimidine synthesis, phospholipid metabolism, and bile acid uptake

Patients should be aware that nausea and diarrhoea may be more troublesome when taking both medications simultaneously

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Their time course and regulation during human liver regeneration remains unknown

Months 7-11: Approaching Plateau Whats happening: Weight loss slows as you approach your new set point