GSH also detoxifies electrophilic xenobiotics compounds (chemical carcinogens, environmental pollutants, drugs, etc.) and their metabolites to GSH adduct (GS-X) in the direct catalysis of glutathione-S-transferase (GST, primary approach) [32]
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Activating both receptors at once (which is what tirzepatide does, unlike single-pathway drugs like Wegovy or Ozempic) intensifies the motility shift and increases secretory activity in the lower bowel
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The food you eat goes through lots of processes before it reaches your bowel and becomes stool