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Oral MTX was stopped due to nausea (n=43), ineffectiveness (n=13) or partial response (n=11), headache (n=3), increased liver enzymes (n=2), and lethargy (n=2)
105 HCC cells also exhibit a marked increase in amino acid metabolism, particularly in the metabolism of glutamine
doi: 10.1152/ajpregu.00565.2004
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