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BPC-157 upregulates VEGFR2 expression in vascular endothelial cells and promotes receptor internalization through endocytosis-dependent mechanisms

Frequency and dosage depend on factors like medical condition, response to treatment, age, diet, and overall health

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Bulk RNA sequencing revealed that gene expression changes were most pronounced in the MBH, where RAMP1/3 KO mice treated with sCT showed extensive differential expression of over 1,700 genes, while WT mice exhibited comparatively minor transcriptional shifts