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Tirzepatide takes this a step further by activating both GLP-1 and GIP (a gut hormone that improves insulin sensitivity and supports fat metabolism) receptors simultaneously
Enhanced bioactivity The arginine substitution at position 3 increases potency in experimental settings
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European Journal of Nutrition
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for managing type 2 diabetes and, at higher doses, for chronic weight management in adults with obesity or overweight with weight-related comorbidities
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