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Trials still pending Two core obesity trials are still running: TRIUMPH-2 (obesity + type 2 diabetes) results expected later 2026 TRIUMPH-3 (obesity + established cardiovascular disease) results expected later 2026 A separate cardiovascular outcomes trial, TRIUMPH-Outcomes (~10,000 patients), is not required for the initial obesity NDA and wont report until 20282029
This lack of precision diluted any potential therapeutic signal
Oral Semaglutide Perfect for needle-phobic patients
This combination is administered via weekly subcutaneous injection, providing a steady release of both semaglutide and cyanocobalamin (B12) into the bloodstream
