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Peptide degradation reduces effectiveness without any visible indication that the product has lost potency, making proper storage a silent but critical factor in protocol outcomes

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Severe gastrointestinal issues: Individuals with a history of severe gastrointestinal problems, such as gastroparesis or pancreatitis, should steer clear of this medication, as semaglutide can exacerbate these conditions

Hydration Levels: Dehydration can sometimes be mistaken for hunger, potentially masking the effects of the medication

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