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Patients and clinicians are advised to watch for severe, ongoing stomach pain, with nausea or vomiting
To evaluate the effect of CI inhibition on growth, organoids were seeded as fragments in Matrigel and treated the following day with water (CTRL), 5 M 5FU, 3 mM metformin or a combination of 5FU and metformin for 72 h
References Albrecht S, Jung S, Mller R, et al
doi: 10.1177/0960327116629529, 89
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