tirzepatide which class What Is Used for? Approved and Potential Uses tirzepatide class Back to routine

2022 Mar 15

There are some oral options available, like Rybelsus or oral Wegovy

Incidence of fractures in patients with type 2 diabetes in the SAVOR-TIMI 53 trial

According to the Medicines and Healthcare products Regulatory Agency (MHRA) and National Institute for Health and Care Excellence (NICE) guidance, it may be prescribed as: Monotherapy when diet and exercise alone do not provide adequate glycaemic control and when metformin is considered inappropriate due to intolerance or contraindications Add-on therapy in combination with other glucose-lowering medications, including metformin, sulfonylureas, sodium-glucose co-transporter-2 (SGLT2) inhibitors, or insulin, when existing treatment does not achieve target HbA1c levels NICE Technology Appraisal 653 (TA653) recommends oral semaglutide as an option for treating type 2 diabetes in adults when a GLP-1 receptor agonist would otherwise be appropriate according to NICE guideline NG28

The SURMOUNT trials examining tirzepatide for weight management showed similar patterns, with gastrointestinal side effects being dose-related and most prominent during the initial titration period