In the CNS, GLP-1s may impact neuronal function in conditions, such as Alzheimer's disease and Parkinson's disease, through multiple mechanisms
Butterfield D, Castegna A, Lauderback C, Drake J
L-Carnitine's muscle-protective effects extend to conditions of oxidative stress and inflammatory challenge
Cautions: Consult a healthcare practitioner prior to use if you are pregnant, breastfeeding or if you have liver disease, kidney disease and/ or a seizure disorder
It demonstrated that GLP-1 receptor agonists significantly increase the risk of gastrointestinal adverse events, with nausea being the most frequently reported outcome, and substantial heterogeneity across agents, particularly for orforglipron, exenatide, tirzepatide, semaglutide, and liraglutide