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MOTS-c has a plasma half-life of approximately 2 hours, but its metabolic effects persist for 68 hours due to downstream signalling cascades
Participants had functional dyspepsia with Helicobacter pylori
Also, Sun et al
Martins et al
Specifically, it upregulates genes involved in collagen synthesis (Types I, III, and V), decorin production (which regulates collagen fibril assembly), integrin and glycosaminoglycan synthesis, DNA repair enzymes, antioxidant defense systems (superoxide dismutase, glutathione), and stem cell markers
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