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The local GI argument is the strongest case for capsules, but it is rarely explained correctly If BPC-157 is degraded locally in the gut lumen and acts on GI epithelial receptors before degradation, then high oral bioavailability is not required for a GI-local effect

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It also highlights the difference between: Muscle area measured by imaging Lean body mass measured by body-composition testing Functional outcomes such as strength, mobility, endurance, and performance Further research is needed before these measurements can be translated into broader functional claims