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The study also looked at the role of inflammation potentially underlying this association
Gut Dysbiosis: Assessing the balance of beneficial vs
In mitochondria, LA is a vital cofactor for several enzymes (the oxoglutarate dehydrogenase complex [OGDC], pyruvate dehydrogenase complex [PDHC], branched-chain -ketoacid dehydrogenase complex [BCKDC]) that contribute to aerobic metabolism and nucleic acid synthesis [32, 33]
The inactivation of GPX4 in cells culminates in phospholipid peroxidation and cell death, which can be mitigated by ferroptosis inhibitors [19]
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