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Here's what we'll cover Key takeaways Fatigue is a known side effect of tirzepatide, although its less common than gastrointestinal side effects, such as nausea and stomach pain

The increased cell turnover also exfoliates the skin without the need to scrub at it, removing dead skin cells and bringing fresh, more even-toned cells to the surface

These results highlight semaglutides early action on decreasing major cardiovascular events, with significant benefits already evident by the first 6 months, and for some, even earlier, even before any major weight loss and before most patients would have been titrated to their full target dose of 2.4 mg, said lead author Dr Jorge Plutzky, Director of Preventive Cardiology, Cardiovascular Medicine at Brigham and Womens Hospital, Boston, MA, USA and a member of SELECT Steering Committee

This is due to the host of associated risks from malnutrition, nausea, and potential issues with taking other oral medications (due to reduced gastric emptying)