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Statements Data availability statement The original contributions presented in the study are publicly available

N Engl J Med 389(12):10691084 Kosiborod MN, Petrie MC, Borlaug BA, Javed B, Davies MJ, Hovingh GK et al (2024) Semaglutide in patients with obesity-related heart failure and type 2 diabetes

29 GST serves as a general S -glutathionylase enzyme and promotes S -glutathionylation

Most adverse effects are gastrointestinal (nausea, vomiting, diarrhea) and tend to lessen with time or dose adjustment ( Current clinical guidelines reflect this evolving evidence