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Vallof et al., 2019a)

Site rotation is essential

To evaluate the effects of the drugs, the statistical differences between the vehicle and drug treatment groups were analyzed using Dunnetts test

Similarly, deleting AMPK1 gene altered the differentiation pathway of M-MDSCs, leading them to adopt a cytotoxic role against tumors through nitric oxide synthase 2, highlighting the central role of AMPK1 in MDSC-mediated immunosuppression