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But in patients with pre-existing inflammatory bowel disease, the inflammatory cascade in the colon may be sensitized or amplified by GLP-1 activation, potentially triggering flares or worsening existing inflammation

Hormonal effects: Obesity-related hormonal changes may affect airway muscle tone

I generally recommend people start with the expectation of reaching maximum dose but remain open to maintenance at lower levels

The PwC analysis of Numerator data has shown an increase of 4% to 6% in apparel categories such as activewear, denim dresses and intimates for GLP-1 households, "driven by a wardrobe replacement and a move toward more form-fitting clothes to match newfound, more confident identifies," said Furman

NES = 7.802) (Figure 4B)