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GLP1 receptor agonists like semaglutide and tirzepatide are not fad-based fixes

de Miguel-Diez, J

Incretin-based therapies are also being investigated in other indications and across several organs, and as such, have completely changed the treatment landscape for a variety of metabolic diseases

Across the HF spectrum, their effects may differ according to phenotype, with potentially greater utility in patients with obesity or HFpEF, whereas their role in established HFrEF remains uncertain and should be individualized pending dedicated outcome trials [22]

The news: Cigna will stop covering GLP-1 drugs for weight loss under its employee health plan starting July 1, per Reuters