Exp Eye Res 1997 Feb
That's expected, not a sign something is wrong
Ex-4 also restores SERCA2a expression and activity via the eNOS/cGMP/PKG pathway, reducing cytoplasmic Ca 2+ levels and suppressing structural remodeling in HF rats [64]
ROS increase the severity of bronchial asthma by activating numerous inflammatory mediators, including leukotrienes B4 (55) and D4, regulated on activation, normal T-cell expressed and secreted (RANTES) chemokines, eotaxins, IL-5 (55), IL-1, -4, -6, GM-CSF, interferon (INF), platelet-activating factor (PAF), tumor necrosis factor (TNFa), adhesion molecules (VCAM-1) (56) and major basic protein (MBP) (57)
Cancers with higher GSH levels were more likely to survive vascular endothelial-induced oxidative and nitrosative stress and metastasize at different sites [60]