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Most clinical trials measured outcomes at 68 weeks, highlighting that this is a long-term intervention

Our findings indicate that patients treated with semaglutide, particularly at higher doses such as Wegovy (2.4 mg), exhibited a higher incidence of psychiatric outcomes compared to non-GLP-1 RA users

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Retatrutide may require particular caution or may not be suitable for individuals with: A personal or family history of medullary thyroid carcinoma (MTC) or Multiple Endocrine Neoplasia syndrome type 2 (MEN2) based on findings in rodent studies, this is a precaution shared across the GLP-1 receptor agonist class in EU and UK product information