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Nat Rev Neurosci

GHK-Cu 1 The activity of GHK-Cu is thought to be multifaceted and includes: GHK-Cu has been associated with the upregulation of genes involved in tissue repair, anti-inflammatory signaling, and antioxidant defense, and the downregulation of genes linked to fibrosis and oxidative stress

Tirzepatide, a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist, targets multiple hormonal pathways involved in metabolic regulation

NNMT metabolizes nicotinamide into 1-methylnicotinamide (MNA), diverting it away from the NAD+ salvage pathway

These findings remain in early exploratory stages and warrant further rigorous study