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Dapagliflozin once-daily and exenatide once-weekly dual therapy: a 24-week randomized, placebo-controlled, phase II study examining effects on body weight and prediabetes in obese adults without diabetes

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In patients with T2DM, the pancreas responds initially by expanding the mass of -cells and increasing insulin secretion to compensate for the increased metabolic demand [1]

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While generally well-tolerated, some patients may experience mild and temporary side effects like nausea, vomiting, or diarrhea