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Peer review Peer review information Communications Medicine thanks Lei Guo and Woo Ri Chae for their contribution to the peer review of this work

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Administration of CBP or LDH inhibitors, or cell-penetrating peptides that can specifically block the lactylation of MRE11, can reduce the lactylation of MRE11, inhibit HR, and enhance the sensitivity of tumor cells to chemotherapeutic agents such as cisplatin, PARPi, etc [26]

Enzymatic Liberation : Once S-Acetyl L-Glutathione reaches target tissues like the liver and lungs, specific esterases cleave off the protective acetyl group, releasing active glutathione directly where your cells need it most for cellular health support

By combining these compounds, GACLIV supports multiple systems at onceenergy production, cellular recovery, and metabolic balance