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Make It Much Harder to Compound GLP-1s Redefine what counts as a copy of a brand-name drug Require pharmacists to prove theres a meaningful difference for each patient Limit pharmacies to compounding certain medications only 20 times per month Clarify that adding something minor like B12 does not make it different enough 2
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For both of these final limitations, the use of rich multimodal clinical data such as clinical notes to assess patient-level features driving motivation for GLP-1 use and discontinuation, as well as imaging to quantify and assess fat loss through CT scans could help shed light on the true impact of GLP-1s on body composition as well as patient profiles that are related to varying levels of treatment effect
