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Nrf2-are pathway: an emerging target against oxidative stress and neuroinflammation in neurodegenerative diseases

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It has been noted that younger children may be less susceptible to APAP-induced hepatotoxicity because of increased glutathione stores or metabolism differences as a result of genetic variability ( N -acetyl- p -benzoquinone imine (NAPQI) and increased hepatotoxicity ( Figure 1 for the pathway)

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