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Cysteine is then used to synthesize GSH, a potent antioxidant, through the action of glutamate-cysteine ligase (GCL) and glutathione synthase (GSS) (Paul et al., 2018)

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This selection may also have influenced the observed adverse event rates, as treatment tolerability and physician familiarity with specific agents may have varied over time, potentially affecting both reporting and management of side effects

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For the separate questions of KLOW dose, frequency, syringe units, and reconstitution, see the KLOW dosing guide