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The peptide operates through multiple interconnected signaling cascades rather than binding to a single identified receptor, which distinguishes it from many pharmaceutical compounds
Journal of Clinical Endocrinology & Metabolism, 91(3), 799-805
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The table below shows dosing for all three formulations: Egrifta SV (the current main product), Egrifta WR (a newer once-weekly-reconstitution version), and legacy Egrifta (the original 2 mg/day product used in trials)
doi:10.1146/annurev.bi.52.070183.003431
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