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tripeptide CAS 49557-75-7) is the copper(II) complex of the naturally occurring human tripeptide glycyl-L-histidyl-L-lysine (GHK) , originally isolated from human plasma in 1973 by Dr

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Upregulated: collagen synthesis genes (COL1A1, COL3A1), antioxidant genes (SOD1, SOD3), DNA repair genes (GADD45A) Downregulated: inflammatory cytokines (IL-6, TNF-), metalloproteinases (MMP-2, MMP-9), pro-fibrotic mediators Net effect: shift from tissue destruction and inflammation toward repair and remodeling This breadth of gene modulation is unusual for a single tripeptide and has generated significant research interest in fields ranging from dermatology to neuroscience