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One participant was on a methylphenidate hydrochloride daily (PRN) dose during the period of testing and reported having treatment free days during school vacation as directed by his physician
In ALS, the dysfunctional uptake of glutamate by astrocytic transporters contributes to excitotoxicity at least in a subset of ALS patients [97], however, simple inhibition of glutamate transport failed to produce an ALS-like condition in animals (see section The classical view: microglia as engines of inflammation for more details)
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