Despite this small heart rate effect, large-scale cardiovascular outcome trials, including the SUSTAIN-6 study, have demonstrated that semaglutide is associated with cardiovascular benefits in people with type 2 diabetes at high cardiovascular risk
The study also examined body composition in greater detail
Leombruni P, Miniotti M, Colonna F, Sica C, Castelli L, Bruzzone M, Parisi S, Fusaro E, Sarzi-Puttini P, Atzeni F, Torta RG
Caffeine is a diuretic, and tirzepatide users already need extra water to manage nausea and support GLP-1 function
Asking your clinician for a scalp evaluation and relevant labs helps separate causes