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Bottom Line: Personally, I was excited by the wide-ranging positive signals for GLP-1 drugs uncovered by this discovery analysis
Things worked
SFUs undergo hepatic metabolism Use with caution in patients with renal insufficiency (increases the risk for hypoglycemia) Some SFUs have active metabolites that undergo renal clearance Caution in elderly patients (in whom hypoglycemia may be especially dangerous) Pharmacokinetics: PO Hepatic metabolism Once a day dosing Side Effects: weight gain the relatively long-acting sulfonylureas stimulate insulin secretion not only during the meal, but for the majority of a day
However bloating and gas at the beginning of SIBO treatment can also be down to diet changes
Why Im Annoyed First, heres why this paper irritated me
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