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National Academy of Medicine
It's just the boundary of what the drug does
In prediabetes, metformin has evidence for delaying progression to type 2 diabetes in selected higher-risk groups, such as younger adults with higher body weight or people with a history of gestational diabetes
Starting at a low dose and titrating up slowly minimizes these effects
Quieting Neuroinflammation Beyond energy metabolism, both pathways converge on neuroinflammation, the activation of the brain's resident immune cells, known as microglia, in response to stress, injury, or metabolic disruption
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